[3] Guayaquil City 0-0 Macara [16] 2022-08-06 22:30
Stadium: Estadio Christian Benitez Betancourt Round: 5
Referee: Roberto Paul Sanchez Rodriguez Home Manager: Pool Gavilanez Away Manager: Paul Velez
Head to Head
| Ekwador - LigaPro Serie A | 2022/03/20 21:30 | Macara v Guayaquil City | L | 2-0 |
| Ekwador - LigaPro Serie A | 2021/07/24 22:30 | Macara v Guayaquil City | W | 0-2 |
| Ekwador - LigaPro Serie A | 2021/02/20 21:30 | Guayaquil City v Macara | W | 3-1 |
| Ekwador - LigaPro Serie A | 2020/11/02 23:30 | Macara v Guayaquil City | D | 1-1 |
| Ekwador - LigaPro Serie A | 2020/03/08 18:45 | Guayaquil City v Macara | D | 1-1 |
| Ekwador - LigaPro Serie A | 2019/07/09 00:15 | Macara v Guayaquil City | L | 2-0 |
| Ekwador - LigaPro Serie A | 2019/02/09 01:00 | Guayaquil City v Macara | D | 1-1 |
| Ekwador - LigaPro Serie A | 2018/12/02 17:00 | Macara v Guayaquil City | L | 6-1 |
| Ekwador - LigaPro Serie A | 2018/07/27 20:00 | Guayaquil City v Macara | D | 1-1 |
| Ekwador - LigaPro Serie A | 2018/05/27 21:00 | Guayaquil City v Macara | L | 0-2 |
| Ekwador - LigaPro Serie A | 2018/04/10 00:15 | Macara v Guayaquil City | L | 2-0 |
| Ekwador - LigaPro Serie A | 2017/09/30 00:30 | Macara v Guayaquil City | W | 0-1 |
| Ekwador - LigaPro Serie A | 2017/09/23 23:00 | Guayaquil City v Macara | L | 0-3 |
| Ekwador - LigaPro Serie A | 2017/05/13 18:00 | Macara v Guayaquil City | L | 2-1 |
| Ekwador - LigaPro Serie A | 2017/04/08 23:30 | Guayaquil City v Macara | W | 3-0 |