[6] Santos Laguna 4-1 Atletico San Luis [9] 2022-08-29 00:05
Stadium: Estadio TSM Corona Round: 11
Referee: Fernando Guerrero Ramirez Home Manager: Eduardo Fentanes Away Manager: Andre Jardine
Head to Head
| Meksyk - Liga MX | 2022/05/01 21:00 | Atletico San Luis v Santos Laguna | W | 1-3 |
| Meksyk - Liga MX | 2021/11/21 01:00 | Santos Laguna v Atletico San Luis | W | 2-0 |
| Meksyk - Liga MX | 2021/11/08 01:06 | Santos Laguna v Atletico San Luis | D | 0-0 |
| Meksyk - Liga MX | 2021/02/19 03:00 | Atletico San Luis v Santos Laguna | L | 1-0 |
| Meksyk - Liga MX | 2020/10/26 01:06 | Santos Laguna v Atletico San Luis | W | 2-1 |
| Meksyk - Liga MX | 2019/09/21 22:00 | Atletico San Luis v Santos Laguna | W | 2-3 |
| Puchar Meksyku | 2015/02/18 01:00 | Santos Laguna v Atletico San Luis | W | 3-0 |
| Puchar Meksyku | 2015/02/04 03:00 | Atletico San Luis v Santos Laguna | D | 0-0 |
| Puchar Meksyku | 2014/08/06 00:00 | Santos Laguna v Atletico San Luis | D | 0-0 |
| Puchar Meksyku | 2014/07/31 00:00 | Atletico San Luis v Santos Laguna | L | 3-1 |