[5] Puebla 5-3 Mazatlan FC [12] 2022-05-08 22:00
Stadium: Estadio Cuauhtemoc Round: 14
Referee: Cesar Arturo Ramos Palazuelos Home Manager: Nicolas Larcamon Away Manager: Gabriel Caballero
Head to Head
| Meksyk - Liga MX | 2022/04/30 02:05 | Mazatlan FC v Puebla | L | 2-1 |
| Meksyk - Liga MX | 2021/10/20 00:00 | Puebla v Mazatlan FC | W | 2-0 |
| Meksyk - Liga MX | 2021/04/03 01:30 | Puebla v Mazatlan FC | W | 3-1 |
| Meksyk - Liga MX | 2020/07/28 03:00 | Mazatlan FC v Puebla | W | 1-4 |
| Meksyk - Liga MX | 2016/04/03 02:30 | Mazatlan FC v Puebla | L | 2-0 |
| Meksyk - Liga MX | 2015/10/04 22:00 | Puebla v Mazatlan FC | L | 1-3 |
| Superpuchar Meksyku | 2015/07/20 22:30 | Puebla v Mazatlan FC | W | 1-0 |
| Meksyk - Liga MX | 2015/02/21 01:30 | Mazatlan FC v Puebla | W | 1-2 |
| Puchar Meksyku | 2014/09/25 00:00 | Mazatlan FC v Puebla | L | 3-0 |
| Puchar Meksyku | 2014/09/17 00:00 | Puebla v Mazatlan FC | W | 2-1 |
| Meksyk - Liga MX | 2014/08/30 22:00 | Puebla v Mazatlan FC | W | 3-2 |