[11] Santos Laguna 2-1 Lobos BUAP [10] 2018-07-22 23:00
Stadium: Estadio TSM Corona Round: 1
Referee: Oscar Mejia Garcia Home Manager: Robert Siboldi Away Manager: Juan Francisco Palencia Hernandez
Head to Head
| Meksyk - Liga MX | 2018/01/08 00:00 | Santos Laguna v Lobos BUAP | W | 4-2 |
| Meksyk - Liga MX | 2017/07/22 22:00 | Lobos BUAP v Santos Laguna | D | 2-2 |
Home History
| Meksyk - Champion of Champions | 2018/07/16 01:00 | Tigres UANL v Santos Laguna | L | 4-0 |
| Meksyk - Liga MX | 2018/05/21 00:00 | Toluca v Santos Laguna | D | 1-1 |
| Meksyk - Liga MX | 2018/05/18 01:00 | Santos Laguna v Toluca | W | 2-1 |
| Meksyk - Liga MX | 2018/05/14 00:00 | Club America v Santos Laguna | D | 2-2 |
| Meksyk - Liga MX | 2018/05/11 00:30 | Santos Laguna v Club America | W | 4-1 |
| Meksyk - Liga MX | 2018/05/06 23:00 | Santos Laguna v Tigres UANL | W | 2-0 |
| Meksyk - Liga MX | 2018/05/04 00:30 | Tigres UANL v Santos Laguna | L | 2-0 |
| Meksyk - Liga MX | 2018/04/29 02:00 | Club America v Santos Laguna | L | 1-0 |
Away History
| Meksyk - Liga MX | 2018/04/28 22:00 | Lobos BUAP v Puebla | L | 0-1 |
| Meksyk - Liga MX | 2018/04/22 00:00 | Monterrey v Lobos BUAP | L | 4-0 |
| Meksyk - Liga MX | 2018/04/14 22:00 | Lobos BUAP v Necaxa | L | 0-1 |
| Meksyk - Liga MX | 2018/04/07 22:00 | Cruz Azul v Lobos BUAP | L | 1-0 |
| Meksyk - Liga MX | 2018/03/31 23:00 | Lobos BUAP v Toluca | L | 1-2 |
| Meksyk - Liga MX | 2018/03/18 01:06 | Leon v Lobos BUAP | D | 2-2 |
| Meksyk - Liga MX | 2018/03/10 23:00 | Lobos BUAP v Chivas Guadalajara | L | 0-1 |
| Puchar Meksyku | 2018/03/08 03:05 | Unam Pumas v Lobos BUAP | L | 3-0 |