Stadium: Shuford Stadium Round: 1
| NCAAF | 2021/11/13 18:00 | Lenoir Rhyne Bears v Catawba Indians | L | 56-3 |
| NCAAF | 2019/11/16 17:00 | Catawba Indians v Lenoir Rhyne Bears | L | 3-49 |
| NCAAF | 2018/11/10 19:00 | Lenoir Rhyne Bears v Catawba Indians | L | 63-21 |
| NCAAF | 2022/10/29 18:00 | Barton Bulldogs v Catawba Indians | L | 38-21 |
| NCAAF | 2022/10/22 22:00 | Catawba Indians v Limestone Saints | L | 23-48 |
| NCAAF | 2022/10/15 22:00 | Catawba Indians v Newberry Wolves | L | 27-34 |
| NCAAF | 2022/10/08 22:00 | Wingate Bulldogs v Catawba Indians | L | 28-0 |
| NCAAF | 2022/09/30 19:00 | Emory And Henry Wasps v Catawba Indians | L | 38-23 |
| NCAAF | 2022/09/24 20:00 | Catawba Indians v Tusculum Pioneers | L | 17-50 |
| NCAAF | 2022/09/17 17:00 | Mars Hill Lions v Catawba Indians | L | 38-7 |
| NCAAF | 2022/09/10 16:00 | Shorter Hawks v Catawba Indians | L | 34-21 |
| NCAAF | 2022/10/29 17:00 | Lenoir Rhyne Bears v Wingate Bulldogs | L | 21-24 |
| NCAAF | 2022/10/22 18:00 | Lenoir Rhyne Bears v Newberry Wolves | L | 24-38 |
| NCAAF | 2022/10/15 20:00 | Barton Bulldogs v Lenoir Rhyne Bears | W | 0-34 |
| NCAAF | 2022/10/08 17:00 | Lenoir Rhyne Bears v Limestone Saints | W | 51-30 |
| NCAAF | 2022/09/30 19:00 | Virginia Wise Highland Cavaliers v Lenoir Rhyne Bears | W | 10-42 |
| NCAAF | 2022/09/24 22:00 | Lenoir Rhyne Bears v Carson–Newman Eagles | W | 34-13 |
| NCAAF | 2022/09/17 20:00 | Erskine Flying Fleet v Lenoir Rhyne Bears | W | 20-42 |
| NCAAF | 2022/09/10 17:00 | Lenoir Rhyne Bears v Ferris State | L | 5-27 |