Home History
| NCAAF | 2021/11/24 00:00 | Buffalo v Ball State | L | 3-20 |
| NCAAF | 2021/11/18 00:00 | Northern Illinois v Buffalo | L | 33-27 |
| NCAAF | 2021/11/10 00:00 | Buffalo v Miami Ohio | L | 18-45 |
| NCAAF | 2021/10/30 16:00 | Bowling Green v Buffalo | L | 56-44 |
| NCAAF | 2021/10/23 19:30 | Buffalo v Akron | W | 45-10 |
| NCAAF | 2021/10/16 16:00 | Ohio v Buffalo | W | 26-27 |
| NCAAF | 2021/10/09 23:00 | Buffalo v Kent State | L | 38-48 |
| NCAAF | 2021/10/02 16:00 | Western Michigan v Buffalo | L | 24-17 |
Away History
| NCAAF - Bowl Games | 2021/12/29 19:15 | Maryland v Virginia Tech | W | 54-10 |
| NCAAF | 2021/11/27 17:00 | Maryland v Rutgers | W | 40-16 |
| NCAAF | 2021/11/20 20:30 | Michigan v Maryland | L | 59-18 |
| NCAAF | 2021/11/13 21:00 | Maryland v Michigan State | L | 21-40 |
| NCAAF | 2021/11/06 19:30 | Penn State v Maryland | L | 31-14 |
| NCAAF | 2021/10/30 16:00 | Indiana v Maryland | W | 35-38 |
| NCAAF | 2021/10/23 19:30 | Maryland v Minnesota | L | 16-34 |
| NCAAF | 2021/10/09 16:00 | Maryland v Ohio State | L | 17-66 |