[15] Santos Laguna 4-0 Tijuana [11] 2022-03-14 01:00
Stadium: Estadio TSM Corona Round: 10
Referee: Brian Omar Gonzalez Veles Home Manager: Eduardo Fentanes Away Manager: Sebastian Mendez
Head to Head
| Meksyk - Liga MX | 2021/09/11 02:06 | Tijuana v Santos Laguna | L | 2-1 |
| Meksyk - Liga MX | 2021/03/14 03:05 | Tijuana v Santos Laguna | W | 0-1 |
| Meksyk - Liga MX | 2020/10/12 00:06 | Santos Laguna v Tijuana | W | 2-0 |
| Meksyk - Liga MX | 2020/01/11 03:10 | Tijuana v Santos Laguna | L | 2-1 |
| Meksyk - Liga MX | 2019/10/19 02:06 | Santos Laguna v Tijuana | W | 4-1 |
| Meksyk - Liga MX | 2019/02/11 00:00 | Santos Laguna v Tijuana | D | 1-1 |
| Meksyk - Liga MX | 2018/08/23 02:06 | Tijuana v Santos Laguna | D | 2-2 |
| Meksyk - Liga MX | 2018/02/04 01:00 | Santos Laguna v Tijuana | D | 0-0 |
Home History
| Meksyk - Liga MX | 2022/03/06 03:00 | Chivas Guadalajara v Santos Laguna | L | 1-0 |
| Meksyk - Liga MX | 2022/03/03 03:00 | Santos Laguna v Unam Pumas | W | 3-2 |
| Meksyk - Liga MX | 2022/02/28 01:00 | Cruz Azul v Santos Laguna | W | 1-2 |
| Puchar Mistrzów CONCACAF | 2022/02/24 01:15 | CF Montreal v Santos Laguna | L | 3-0 |
| Meksyk - Liga MX | 2022/02/19 03:00 | Juarez FC v Santos Laguna | D | 0-0 |
| Puchar Mistrzów CONCACAF | 2022/02/16 03:00 | Santos Laguna v CF Montreal | W | 1-0 |
| Meksyk - Liga MX | 2022/02/13 03:00 | Santos Laguna v Club America | L | 2-3 |
| Meksyk - Liga MX | 2022/02/07 00:00 | Atlas v Santos Laguna | L | 2-1 |
Away History
| Meksyk - Liga MX | 2022/03/02 01:00 | Toluca v Tijuana | W | 1-2 |
| Meksyk - Liga MX | 2022/02/26 03:06 | Tijuana v Atlas | W | 2-0 |
| Meksyk - Liga MX | 2022/02/19 03:06 | Tijuana v Necaxa | D | 1-1 |
| Meksyk - Liga MX | 2022/02/12 01:00 | Mazatlan FC v Tijuana | L | 2-0 |
| Meksyk - Liga MX | 2022/02/06 03:06 | Tijuana v Unam Pumas | W | 1-0 |
| Meksyk - Liga MX | 2022/01/29 03:00 | Puebla v Tijuana | L | 3-1 |
| Meksyk - Liga MX | 2022/01/16 03:06 | Tijuana v Leon | D | 1-1 |
| Meksyk - Liga MX | 2022/01/09 03:00 | Cruz Azul v Tijuana | L | 2-0 |