[30] Karen Khachanov 3-6,2-6,6-3,1-6 Rafael Nadal [5] 2022-01-21 10:10
Stadium: Rod Laver Arena Round: 25 Ground: Hardcourt outdoor
Head to Head
| Mubadala World Tennis Championship | 2019/12/20 15:15 | Rafael Nadal v Karen Khachanov | 6-1,6-3 |
| Puchar Davisa | 2019/11/19 20:05 | Rafael Nadal v Karen Khachanov | 6-3,7-6 |
| ATP Indian Wells | 2019/03/15 20:30 | Karen Khachanov v Rafael Nadal | 6-7,6-7 |
| US Open | 2018/08/31 18:20 | Rafael Nadal v Karen Khachanov | 5-7,7-5,7-6,7-6 |
| ATP Toronto | 2018/08/12 02:15 | Rafael Nadal v Karen Khachanov | 7-6,6-4 |
| ATP Monte Carlo | 2018/04/19 14:20 | Rafael Nadal v Karen Khachanov | 6-3,6-2 |
| ATP Pekin | 2017/10/05 08:30 | Rafael Nadal v Karen Khachanov | 6-3,6-3 |
| Wimbledon | 2017/07/07 14:25 | Rafael Nadal v Karen Khachanov | 6-1,6-4,7-6 |
Home History
| Australian Open | 2022/01/19 07:30 | Karen Khachanov v Benjamin Bonzi | 6-4,6-0,7-5 |
| Australian Open | 2022/01/17 02:00 | Karen Khachanov v Denis Kudla | 3-6,6-3,6-2,7-6 |
| ATP Adelaide 2 | 2022/01/13 00:30 | Karen Khachanov v Arthur Rinderknech | 6-7,5-7 |
| ATP Adelaide 2 | 2022/01/12 03:35 | Karen Khachanov v Gianluca Mager | 7-5,6-3 |
| ATP Adelaide | 2022/01/09 07:30 | Gael Monfils v Karen Khachanov | 6-4,6-4 |
| ATP Adelaide | 2022/01/08 05:10 | Marin Čilić v Karen Khachanov | 6-7,3-6 |
| ATP Adelaide | 2022/01/07 06:35 | Egor Gerasimov v Karen Khachanov | 5-7,3-6 |
| ATP Adelaide | 2022/01/06 03:50 | Steve Johnson v Karen Khachanov | 4-6,6-4,2-6 |
Away History
| Australian Open | 2022/01/19 02:45 | Yannick Hanfmann v Rafael Nadal | 2-6,3-6,4-6 |
| Australian Open | 2022/01/17 03:35 | Marcos Giron v Rafael Nadal | 1-6,4-6,2-6 |
| ATP Melbourne | 2022/01/09 08:15 | Rafael Nadal v Maxime Cressy | 7-6,6-3 |
| ATP Melbourne | 2022/01/08 10:40 | Rafael Nadal v Emil Ruusuvuori | 6-4,7-5 |
| ATP Melbourne | 2022/01/06 03:50 | Rafael Nadal v Ricardas Berankis | 6-2,7-5 |
| Mubadala World Tennis Championship | 2021/12/18 13:00 | Rafael Nadal v Denis Shapovalov | 7-6,3-6,6-10 |
| Mubadala World Tennis Championship | 2021/12/17 15:00 | Rafael Nadal v Andy Murray | 3-6,5-7 |
| ATP Washington | 2021/08/05 23:00 | Rafael Nadal v Lloyd Harris | 4-6,6-1,4-6 |