[12] Texas San Antonio 52-46 Western Kentucky [107] 2021-10-09 23:00
Stadium: Houchens Industries-L.T. Smith Stadium Round: 1
Home Manager: Tyson Helton Away Manager: Jeff Traylor
Home History
| NCAAF | 2021/10/02 22:00 | UNLV v Texas-San Antonio | W | 17-24 |
| NCAAF | 2021/09/25 19:30 | Texas-San Antonio v Memphis | W | 31-28 |
| NCAAF | 2021/09/18 22:00 | Middle Tennessee St. v Texas-San Antonio | W | 13-27 |
| NCAAF | 2021/09/11 22:00 | Lamar v Texas-San Antonio | W | 0-54 |
| NCAAF | 2021/09/04 23:30 | Texas-San Antonio v Illinois | W | 37-30 |
| NCAAF | 2020/12/26 20:30 | Lafayette v Texas-San Antonio | L | 31-24 |
| NCAAF | 2020/11/28 20:00 | North Texas v Texas-San Antonio | W | 17-49 |
| NCAAF | 2020/11/21 20:00 | Texas-San Antonio v Southern Mississippi | W | 23-20 |
Away History
| NCAAF | 2021/10/02 23:30 | Western Kentucky v Michigan State | L | 31-48 |
| NCAAF | 2021/09/26 00:00 | Indiana v Western Kentucky | L | 33-31 |
| NCAAF | 2021/09/11 15:30 | Western Kentucky v Army | L | 35-38 |
| NCAAF | 2021/09/03 00:00 | Tennessee Martin v Western Kentucky | W | 21-59 |
| NCAAF | 2020/12/26 20:30 | Western Kentucky v Georgia State | L | 21-39 |
| NCAAF | 2020/12/06 17:00 | Western Kentucky v Charlotte | W | 37-19 |
| NCAAF | 2020/11/21 19:00 | Florida Intl v Western Kentucky | W | 21-38 |
| NCAAF | 2020/11/14 20:30 | Southern Mississippi v Western Kentucky | W | 7-10 |