[3] Rafael Nadal 6-0,2-6,6-2 Kei Nishikori [39] 2021-04-22 14:00
Stadium: Pista Rafa Nadal Round: 26 Ground: Clay
Head to Head
| French Open | 2019/06/04 13:30 | Kei Nishikori v Rafael Nadal | 1-6,1-6,3-6 |
| ATP Monte Carlo | 2018/04/22 12:30 | Rafael Nadal v Kei Nishikori | 6-3,6-2 |
| ATP Barcelona | 2016/04/24 15:30 | Rafael Nadal v Kei Nishikori | 6-4,7-5 |
| ATP Montreal | 2015/08/15 01:40 | Rafael Nadal v Kei Nishikori | 2-6,4-6 |
Home History
| ATP Barcelona | 2021/04/21 14:00 | Rafael Nadal v Ilya Ivashka | 3-6,6-2,6-4 |
| ATP Monte Carlo | 2021/04/16 15:30 | Andrey Rublev v Rafael Nadal | 6-2,4-6,6-2 |
| ATP Monte Carlo | 2021/04/15 13:30 | Grigor Dimitrov v Rafael Nadal | 1-6,1-6 |
| ATP Monte Carlo | 2021/04/14 12:25 | Federico Delbonis v Rafael Nadal | 1-6,2-6 |
| Australian Open | 2021/02/17 08:30 | Stefanos Tsitsipas v Rafael Nadal | 3-6,2-6,7-6,6-4,7-5 |
| Australian Open | 2021/02/15 04:10 | Fabio Fognini v Rafael Nadal | 3-6,4-6,2-6 |
| Australian Open | 2021/02/13 09:45 | Cameron Norrie v Rafael Nadal | 5-7,2-6,5-7 |
| Australian Open | 2021/02/11 10:35 | Michael Mmoh v Rafael Nadal | 1-6,4-6,2-6 |
Away History
| ATP Barcelona | 2021/04/21 15:00 | Kei Nishikori v Cristian Garin | 7-6,4-6,6-1 |
| ATP Barcelona | 2021/04/19 13:10 | Kei Nishikori v Guido Pella | 4-6,7-6,6-2 |
| ATP Miami | 2021/03/29 23:00 | Kei Nishikori v Stefanos Tsitsipas | 3-6,6-3,1-6 |
| ATP Miami | 2021/03/27 15:00 | Kei Nishikori v Aljaz Bedene | 7-6,5-7,6-4 |
| ATP Dubaj | 2021/03/18 15:35 | Lloyd Harris v Kei Nishikori | 6-1,3-6,6-3 |
| ATP Dubaj | 2021/03/17 15:00 | Aljaz Bedene v Kei Nishikori | 4-6,4-6 |
| ATP Dubaj | 2021/03/16 15:00 | Kei Nishikori v David Goffin | 6-3,7-6 |
| ATP Dubaj | 2021/03/14 10:00 | Kei Nishikori v Reilly Opelka | 3-6,6-3,6-4 |